医学毕业论文范文--急诊介入治疗高危不稳定性心绞痛的临床研究

(《中国全科医学》 2003年 第6卷 第12期)
袁义强  刘怀霖  王瑞敏  孙运  于力  郭应先

摘要 目的 研究急诊介入治疗高危不稳定性心绞痛(UAP)的效果及安全性。方法 71例UAP患者入院后随机分为两组:急诊介入治疗组,为43例患者;非急诊介入治疗组,为28例患者。均行冠脉造影和介入治疗。观察30天内心脏事件(包括心绞痛、急性心肌梗死、猝死、再次介入治疗及冠脉搭桥手术)的发生率,症状缓解率,症状缓解时间,住院时间及住院费用。结果 急诊介入治疗与非急诊介入治疗组比较,急诊介入治疗UAP降低了30天内心脏事件(心绞痛、急性心肌梗死、猝死)的发生,p<0.05;缩短了症状缓解及住院时间,p<0.05;降低住院费用,p<0.05;而手术的成功率及疗效相似,p>0.05。结论 急诊介入治疗高危的UAP患者效果好,安全,并可缩短住院时间,降低住院费用。

关键词

The Clinical Study of Emergent Intervention for High Risk Unstable Angina Pectoris

Yuan Yiqiang, Liu Huailin, Ma Yexin, et al. Department of Cardiology, Zhengzhou Seventh People抯 Hospital, Zhengzhou, 450006, P.R.China

Abstract Objective To study the efficacy and safety of intervention for high risk unstable angina pectoris(UAP). Methods 71 patients with high risk UAP were randomized divided into two groups: emergent interventional groups, 43 patients; non-emergent interventional groups,28 patients; All the patients were performed coronary angiography and intervention. The cardiac events(including angina pectoris, acute myocardial infarction, sudden death, reintervention and coronary artery bridge graft) in 30 days, symptom relief rate, symptom relief time, duration of hospitalization and hospitalization expenditure were recorded. Results Emergent intervention decreased cardiac event ( angina pectoris, acute myocardial infarction, sudden death) rates in 30 days, p<0.05, shortened symptom relief and hospitalization time, p<0.05,decreased hospitalization expenditure, p<0.05,. But the procedural success rates and the efficacy were identical with non-emergent intervention group, p>0.05. Conclusion Emergent intervention for high risk unstable angina pectoris is effective, safe, and also can shorten hospitalization time, decrease expenditure.

Key words Unstable, angina pectoris; Intervention; Coronary angiography

  不稳定性心绞痛(UAP)是介入稳定性心绞痛(AP)和急性心肌梗死(AMI)之间的一组临床心绞痛综合征,其包括多种亚型,其中高危组UAP危害最大,如何处理该类患者目前尚有争议。本研究观察了急诊介入治疗高危不稳定性心绞痛的临床结果,并与药物强化治疗后行介入治疗的临床结果进行对比研究。

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